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NaV1.2/1.6 channel blocker-1
CAS No. 1199944-04-1
NaV1.2/1.6 channel blocker-1( —— )
Catalog No. M36447 CAS No. 1199944-04-1
NaV1.2/1.6 channel blocker-1 is a potent inhibitor of NaV1.2 and NaV1.6 channels, exhibiting inhibitory effects on rNaV1.6 and hNaV1.2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 52 | Get Quote |
|
| 5MG | 74 | Get Quote |
|
| 10MG | 113 | Get Quote |
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| 25MG | 220 | Get Quote |
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| 50MG | 327 | Get Quote |
|
| 100MG | 474 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameNaV1.2/1.6 channel blocker-1
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NoteResearch use only, not for human use.
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Brief DescriptionNaV1.2/1.6 channel blocker-1 is a potent inhibitor of NaV1.2 and NaV1.6 channels, exhibiting inhibitory effects on rNaV1.6 and hNaV1.2.
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DescriptionNaV1.2/1.6 channel blocker-1 is a potent NaV1.2/1.6 channel blocker, with IC50s of 9.8 and 24.4 μM for rNaV1.6 and hNaV1.2, respectively. NaV1.2/1.6 channel blocker-1 can be used for the research of generalized epilepsy.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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RecptorSodium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number1199944-04-1
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Formula Weight258.34
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Molecular FormulaC14H14N2OS
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Purity>98% (HPLC)
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Solubility——
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SMILESS=C1OC=2C=CC=CC2C3=NC(=C(N13)CCC)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Rivara M, et, al. Biological Evaluation of Imidazobenzoxazines, Imidazobenzoxazin-5-ones and Imidazobenzoxazin-5-thiones as Sodium Channel Blockers. Letters in Drug Design & Discovery, 2014, 11, 90-97.
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