11β-HSD1 inibitor 19
CAS No. 946400-19-7
11β-HSD1 inibitor 19( —— )
Catalog No. M36393 CAS No. 946400-19-7
11β-HSD1 inibitor 19 shows inhibitory activities for hHSD1 and mHSD1 with IC50s of 16 nM and 10 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 331 | In Stock |
|
| 10MG | 451 | In Stock |
|
| 25MG | 634 | In Stock |
|
| 50MG | 768 | In Stock |
|
| 100MG | 977 | In Stock |
|
| 200MG | 1274 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name11β-HSD1 inibitor 19
-
NoteResearch use only, not for human use.
-
Brief Description11β-HSD1 inibitor 19 shows inhibitory activities for hHSD1 and mHSD1 with IC50s of 16 nM and 10 nM.
-
Description11β-HSD1 inibitor 19 shows inhibitory activities for hHSD1 and mHSD1 with IC50s of 16 nM and 10 nM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetDehydrogenase
-
RecptorDehydrogenase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number946400-19-7
-
Formula Weight461.86
-
Molecular FormulaC19H16ClF4N3O2S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC(F)(F)(F)C1=C(N2C[C@@H](C)N(S(=O)(=O)C3=C(Cl)C=C(C#N)C=C3)CC2)C=CC(F)=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
DHODH-IN-11
DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.A compound structurally related to leflunomide was designed, which contained furan ring (compound 14a).
-
DSM421
DSM421 (DSM-421) is a dihydrodehydrogenase inhibitor (DHODH) that is in preclinical development as a potential treatment option for malaria and has shown activity against field isolates of both P. falciparum and P. vivax.
-
DSM265
DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity (IC50: 8.9 nM).DSM265 inhibits the growth of Pf3D7 parasites and can be used for the treatment and prophylaxis of malaria infections.
Cart
sales@molnova.com