GTP-14564( —— )

Catalog No. M36386 CAS No. 34823-86-4

GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3.

Purity : >98% (HPLC)

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2MG	32	In Stock
5MG	56	In Stock
10MG	102	In Stock
25MG	207	In Stock
50MG	323	In Stock
100MG	465	In Stock
200MG	641	In Stock
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Biological Information

Product Name

GTP-14564
Note

Research use only, not for human use.
Brief Description

GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3.
Description

GTP-14564 is a tyrosine kinase inhibitor targeting to internal tandem duplication (ITD) and FLT3. GTP-14564 inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

Tyrosinase
Recptor

Tyrosine Kinases | FLT
Research Area

——
Indication

——

Chemical Information

CAS Number

34823-86-4
Formula Weight

234.25
Molecular Formula

C15H10N2O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (533.62 mM; Ultrasonic (<60°C)
SMILES

C12=C(C=3C(O1)=CC=CC3)NN=C2C4=CC=CC=C4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Murata K, et al. Selective cytotoxic mechanism of GTP-14564, a novel tyrosine kinase inhibitor in leukemia cells expressing a constitutively active Fms-like tyrosine kinase 3 (FLT3). J Biol Chem. 2003 Aug 29;278(35):32892-8.?

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