Cart
sales@molnova.com
GTP-14564
CAS No. 34823-86-4
GTP-14564( —— )
Catalog No. M36386 CAS No. 34823-86-4
GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 32 | In Stock |
|
| 5MG | 56 | In Stock |
|
| 10MG | 102 | In Stock |
|
| 25MG | 207 | In Stock |
|
| 50MG | 323 | In Stock |
|
| 100MG | 465 | In Stock |
|
| 200MG | 641 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGTP-14564
-
NoteResearch use only, not for human use.
-
Brief DescriptionGTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3.
-
DescriptionGTP-14564 is a tyrosine kinase inhibitor targeting to internal tandem duplication (ITD) and FLT3. GTP-14564 inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayProteasome/Ubiquitin
-
TargetTyrosinase
-
RecptorTyrosine Kinases | FLT
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number34823-86-4
-
Formula Weight234.25
-
Molecular FormulaC15H10N2O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (533.62 mM; Ultrasonic (<60°C)
-
SMILESC12=C(C=3C(O1)=CC=CC3)NN=C2C4=CC=CC=C4
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Murata K, et al. Selective cytotoxic mechanism of GTP-14564, a novel tyrosine kinase inhibitor in leukemia cells expressing a constitutively active Fms-like tyrosine kinase 3 (FLT3). J Biol Chem. 2003 Aug 29;278(35):32892-8.?
molnova catalog
related products
-
NDI-034858
NDI-034858 (TAK-279) is a tyrosine kinase 2 (TYK2) inhibitor (Kd<200 pM) that targets the JH2 structural domain of Tyk2 for the treatment of autoimmune diseases caused by aberrant expression of IL12 and IL23.
-
ethyl rosmarinate
Methyl rosmarinate inhibit the activity of tyrosinase, α-glucosidase, and matrix metalloproteinase-1 (MMP-1).
-
Oxyresveratrol 2-O-β...
Oxyresveratrol 2-O-β-D-glucopyranoside is a phenolic compound isolated from Morus nigra root and is an effective tyrosinase inhibitor with an IC50 of 29.75 μM.
