Cart
sales@molnova.com
ITF3756
CAS No. 2247608-27-9
ITF3756( —— )
Catalog No. M36305 CAS No. 2247608-27-9
ITF3756 is a selective HDAC6 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 89 | In Stock |
|
| 10MG | 136 | In Stock |
|
| 25MG | 244 | In Stock |
|
| 50MG | 347 | In Stock |
|
| 100MG | 490 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameITF3756
-
NoteResearch use only, not for human use.
-
Brief DescriptionITF3756 is a selective HDAC6 inhibitor.
-
DescriptionITF 3756 is a potent and selective HDAC6 inhibitor. ITF 3756 reduces in vitro the expression of PD-L1 on human monocytes and on CD8 T cells, and shows anti-tumor activity.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetHDAC
-
RecptorHDAC
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2247608-27-9
-
Formula Weight301.32
-
Molecular FormulaC13H11N5O2S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (414.84 mM; Ultrasonic )
-
SMILESC(N1C(=NN=N1)C2=CC=CS2)C3=CC=C(C(NO)=O)C=C3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Gianluca Fossati, et al. Abstract 1358: The selective HDAC6 inhibitor ITF3756 stimulates an antitumor immune response and leads to tumor regression in combination with anti CTLA-4 antibody in a colon carcinoma murine model. Cancer Res (2022) 82 (12_Supplement): 1358.
molnova catalog
related products
-
Resminostat
A potent inhibitor of HDAC1/3/6 with IC50s of 43-72 nM.
-
Chidamide
Chidamide(CS055; HBI-8000) is a class I HDAC inhibitor with IC50s of 95/160/67/733 nM for HDAC1/2/3/8; also inhibits HDAC10/11(IC50=78/432 nM).
-
CUDC-101
A potent, multi-targeted HDAC, EGFR and HER2 inhibitor with IC50 of 4.4, 2.4, and 15.7 nM, respectively.
