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ITF3756
CAS No. 2247608-27-9
ITF3756( —— )
Catalog No. M36305 CAS No. 2247608-27-9
ITF3756 is a selective HDAC6 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 97 | Get Quote |
|
| 5MG | 148 | Get Quote |
|
| 10MG | 227 | Get Quote |
|
| 25MG | 394 | Get Quote |
|
| 50MG | 573 | Get Quote |
|
| 100MG | 790 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameITF3756
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NoteResearch use only, not for human use.
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Brief DescriptionITF3756 is a selective HDAC6 inhibitor.
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DescriptionITF 3756 is a potent and selective HDAC6 inhibitor. ITF 3756 reduces in vitro the expression of PD-L1 on human monocytes and on CD8 T cells, and shows anti-tumor activity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC
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Research Area——
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Indication——
Chemical Information
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CAS Number2247608-27-9
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Formula Weight301.32
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Molecular FormulaC13H11N5O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (414.84 mM; Ultrasonic )
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SMILESC(N1C(=NN=N1)C2=CC=CS2)C3=CC=C(C(NO)=O)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gianluca Fossati, et al. Abstract 1358: The selective HDAC6 inhibitor ITF3756 stimulates an antitumor immune response and leads to tumor regression in combination with anti CTLA-4 antibody in a colon carcinoma murine model. Cancer Res (2022) 82 (12_Supplement): 1358.
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