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SS-208
CAS No. 2245942-72-5
SS-208( SS208 )
Catalog No. M26826 CAS No. 2245942-72-5
SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 112 | In Stock |
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| 10MG | 179 | In Stock |
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| 25MG | 312 | In Stock |
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| 50MG | 439 | In Stock |
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| 100MG | 603 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSS-208
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NoteResearch use only, not for human use.
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Brief DescriptionSS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.
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DescriptionSS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.(In Vivo):In C57BL/6 mice injected immunogenic murine SM1 melanoma cells, SS-208 (25 mg/kg; i.p.) causes a significant reduction of the tumor growth.
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In Vitro——
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In VivoSS-208 (25 mg/kg, ip) significantly reduces the tumor growth in melanoma murine model. Animal Model:C57BL/6 mice injected immunogenic murine SM1 melanoma cells subcutaneously.Dosage:25 mg/kg.Administration:IP on day 4, 7, 12, 15 and 18.Result:Significantly reduced the tumor growth.
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SynonymsSS208
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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Recptor5-HT2
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Research Area——
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Indication——
Chemical Information
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CAS Number2245942-72-5
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Formula Weight344.15
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Molecular FormulaC13H11Cl2N3O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (363.21 mM)
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SMILESONC(=O)c1cc(CCNC(=O)c2ccc(Cl)c(Cl)c2)on1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Gonyou HW, et al. Effects of amperozide and azaperone on aggression and productivity of growing-finishing pigs. J Anim Sci. 1988 Nov;66(11):2856-64.
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