Cart
sales@molnova.com
PU-H71 HCl
CAS No. 2095432-24-7
PU-H71 HCl( —— )
Catalog No. M36291 CAS No. 2095432-24-7
PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 296 | Get Quote |
|
| 5MG | 409 | Get Quote |
|
| 10MG | 604 | Get Quote |
|
| 25MG | 908 | Get Quote |
|
| 50MG | 1251 | Get Quote |
|
| 100MG | 1647 | Get Quote |
|
| 500MG | 3312 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamePU-H71 HCl
-
NoteResearch use only, not for human use.
-
Brief DescriptionPU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT.
-
DescriptionPU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT. PU-H71 HCL shows antitumor activity in many preclinical models of malignancy. PU-H71 HCL has an inhibitory effect on the protein expression levels of Rad51 and Ku70, which may be associated with the double chain break repair in the homologous recombination pathway and non-homologous end-joining pathway.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetHSP
-
RecptorHSP | DNA/RNA Synthesis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2095432-24-7
-
Formula Weight548.83
-
Molecular FormulaC18H22ClIN6O2S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCl.IC=1C=C2OCOC2=CC1SC3=NC=4C(=NC=NC4N3CCCNC(C)C)N
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
DN401
DN401 is a potent TRAP1 and Hsp90 Inhibitor( IC50 = 79 nM for TRAP1, IC50 = 698 nM for Hsp90) with potent anticancer activity.
-
IPI-493
IPI-493 (17-amino17demethoxy) is a novel HSP90 inhibitor with antitumor activity.
-
Momordin Ic
Momordin Ic might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways.
