Tallimustine HCl
CAS No. 118438-45-2
Tallimustine HCl( —— )
Catalog No. M36233 CAS No. 118438-45-2
Tallimustine HCl is a DNA inhibitor, an AT-specific alkylated antitumor derivative of diamycin.Tallimustine HCl can be used in severe combined immunodeficiency mouse models of adult myelogenous leukemia, which can be used for the treatment of leukemia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 296 | Get Quote |
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| 5MG | 409 | Get Quote |
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| 10MG | 604 | Get Quote |
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| 25MG | 908 | Get Quote |
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| 50MG | 1251 | Get Quote |
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| 100MG | 1647 | Get Quote |
|
| 500MG | 3312 | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameTallimustine HCl
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NoteResearch use only, not for human use.
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Brief DescriptionTallimustine HCl is a DNA inhibitor, an AT-specific alkylated antitumor derivative of diamycin.Tallimustine HCl can be used in severe combined immunodeficiency mouse models of adult myelogenous leukemia, which can be used for the treatment of leukemia.
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DescriptionTallimustine HCl is a DNA inhibitor, an AT-specific alkylated antitumor derivative of diamycin.Tallimustine HCl can be used in severe combined immunodeficiency mouse models of adult myelogenous leukemia, which can be used for the treatment of leukemia.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA
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Research Area——
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Indication——
Chemical Information
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CAS Number118438-45-2
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Formula Weight734.08
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Molecular FormulaC32H39Cl3N10O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.O=C(NC=1C=C(C(=O)NC=2C=C(C(=O)NC=3C=C(C(=O)NCCC(=N)N)N(C3)C)N(C2)C)N(C1)C)C4=CC=C(C=C4)N(CCCl)CCCl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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JH-RE-06
JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 also improves chemotherapy.
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Calf thymus DNA
Calf thymus DNA (DNA from calf thymus, Thymonucleic acid) is a high-quality double-stranded template DNA extracted from the bovine thymus gland, widely used in studying DNA binding anticancer agents and DNA binding agents that regulate DNA structure and function.
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T2AA
T2AA is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-box peptide interaction.
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