Pirodomast

Research use only, not for human use.

Pirodomast is a thromboxane A (TXA2) synthase inhibitor.

Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is weakly or ineffectively antagonistic to guinea pig bronchospasm induced by histamine, methacholine, serotonin, LTC4, or platelet-activating factor. Pirodomast is a potential antiallergic compound. Pirodomast had only weak relaxant activity on guinea pig trachea in vitro. Pirodomast is a potential antiallergic compound that inhibits the protein hydrolyzing activity of trypsin in vitro, prevents antigen-induced immediate and late asthmatic responses in allergic sheep in vivo, and inhibits antigen-induced airway hyperresponsiveness to histamine and carbachol in allergic sheep.

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Autophagy

Thrombin

Thrombin | Serine Protease

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108310-20-9

307.35

C18H17N3O2

>98% (HPLC)

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O=C1N(C=2C(C(=O)C1N3CCCC3)=CC=CN2)C4=CC=CC=C4

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(-20℃)

With Ice Pack

≥ 2 years