ISX-3

CAS No. 912789-08-3

ISX-3( —— )

Catalog No. M36030 CAS No. 912789-08-3

ISX-3 is a potent pro-osteogenic and anti-adipogenic agent. ISX-3 can increase the expression of PPARγ. ISX-3 can be for the research of osteopenia and osteoporosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 55 In Stock
5MG 41 In Stock
10MG 69 In Stock
25MG 136 In Stock
50MG 217 In Stock
100MG 322 In Stock
200MG 461 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ISX-3
  • Note
    Research use only, not for human use.
  • Brief Description
    ISX-3 is a potent pro-osteogenic and anti-adipogenic agent. ISX-3 can increase the expression of PPARγ. ISX-3 can be for the research of osteopenia and osteoporosis.
  • Description
    ISX-3 is a potent anti-adipogenic and pro-osteogenic agent. ISX-3 increases the expression of PPARγ. ISX-3 has the potential for the research of osteopenia and osteoporosis.
  • In Vitro
    Western Blot Analysis Cell Line:hBMSCs Concentration:50 μM Incubation Time:2 days Result:Increased the PPARγ expression level in the presence of MDI (0.5 mM isobutyl methylxanthine, 1 μM dexamethasone and 1 μM insulin).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    912789-08-3
  • Formula Weight
    330.77
  • Molecular Formula
    C16H15ClN4O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (302.32 mM; Ultrasonic )
  • SMILES
    Clc1cccc(c1)-c1cc(no1)C(=O)NCCCn1ccnc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Nawa K, et al. Discovering small molecules that inhibit adipogenesis and promote osteoblastogenesis: unique screening and Oncostatin M-like activity. Differentiation. 2013 Jul-Sep;86(1-2):65-74.?
molnova catalog
related products
  • Isothymusin

    Isothymusin( MIC= 200 microg/mL) exhibits inhibition activity against Mycobacterium tuberculosis. It ( IC50=7.7 microg/mL ) exhibits antioxidant activity against the radical scavenging ability of DPPH.

  • Kaempferol 7-O-rhamn...

    Kaempferol 7-O-rhamnoside is a natural product from Maytenus hookeri.

  • Org41841

    Org41841 is an agonist of luteinising hormone/chorionic gonadotropin receptor and thyroid stimulating hormone receptor (EC50s: 0.2 and 7.7 μM, respectively) and can be used to study hyperthyroidism.