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ALDH2 modulator 1

CAS No. 1629615-99-1

ALDH2 modulator 1( —— )

Catalog No. M36013 CAS No. 1629615-99-1

ALDH2 modulator 1 is a potent, orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 124 In Stock
5MG 117 In Stock
10MG 185 In Stock
25MG 305 In Stock
50MG 418 In Stock
100MG 559 In Stock
200MG 755 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    ALDH2 modulator 1
  • Note
    Research use only, not for human use.
  • Brief Description
    ALDH2 modulator 1 is a potent, orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.
  • Description
    ALDH2 modulator 1 is a potent and orally active aldehyde dehydrogenase-2 (ALDH2) modulator. ALDH2 modulator 1 reduces blood alcohol levels in mice.
  • In Vitro
    ——
  • In Vivo
    Animal Model:8-9 weeks, 20-22 g, Male C57BL6 mice (treated with PO 5/kg of EtOH) Dosage:40, 60 mg/kg for p.o. or 10 mg/kg for i.v.Administration:P.o. or i.v.Result:Reduced blood alcohol levels in mice treated with PO 5 g/kg of EtOH.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    Dehydrogenase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1629615-99-1
  • Formula Weight
    364.8
  • Molecular Formula
    C18H18ClFN2O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O(CC1CC1)C2=C(C(NCC3=CC(F)=C(OC)C=C3)=O)C(Cl)=CC=N2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wenjin Yang, et al. Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof. WO2014160185A2.
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