Teriflunomide

CAS No. 108605-62-5

Teriflunomide( A77 1726 | HMR 1726 | teriflunomide | Brande name: Aubagio. )

Catalog No. M10335 CAS No. 108605-62-5

Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
50MG 29 In Stock
100MG 45 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Teriflunomide
  • Note
    Research use only, not for human use.
  • Brief Description
    Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis.
  • Description
    Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio and is indicated for the treatment of multiple sclerosis, specifically relapsing forms.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    A77 1726 | HMR 1726 | teriflunomide | Brande name: Aubagio.
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    Dihydroorotate Dehydrogenase
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    108605-62-5
  • Formula Weight
    270.21
  • Molecular Formula
    C12H9F3N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 1 mg/mL ,1; Water: <1 mg/mL (<1 mM); DMSO: 32 mg/mL (118.42 mM)
  • SMILES
    C/C(O)=C(C#N)/C(NC1=CC=C(C(F)(F)F)C=C1)=O
  • Chemical Name
    (Z)-2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide.

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Palmer AM. Curr Opin Investig Drugs. 2010 Nov;11(11):1313-23.
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