GI-560192

CAS No. 301326-41-0

GI-560192( —— )

Catalog No. M35797 CAS No. 301326-41-0

GI-560192 (RL-0070933) is a potent smo cilial modulator with an EC50 value of 0.02 μM. GI-560192 modulates the translocation and/or accumulation of smoothened to the primary cilia by hedgehog signaling pathway.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 174 In Stock
5MG 179 In Stock
10MG 263 In Stock
25MG 392 In Stock
50MG 539 In Stock
100MG 736 In Stock
200MG 986 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    GI-560192
  • Note
    Research use only, not for human use.
  • Brief Description
    GI-560192 (RL-0070933) is a potent smo cilial modulator with an EC50 value of 0.02 μM. GI-560192 modulates the translocation and/or accumulation of smoothened to the primary cilia by hedgehog signaling pathway.
  • Description
    RL-0070933 is a potent smo cilial modulator with an EC50 value of 0.02 μM. RL-0070933 modulates the translocation and/or accumulation of smoothened to the primary cilia by hedgehog signaling pathway.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Wnt/Notch/Hedgehog
  • Target
    Smoothened (Smo)
  • Recptor
    Smo
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    301326-41-0
  • Formula Weight
    316.35
  • Molecular Formula
    C20H16N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(=NNC(=O)C1=CC=C(O)C=C1)C2=CC=C(C=C2)C3=CC=CC=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yu Wang, et al. Modulators of hedgehog signaling pathway. US20130274233A1.
molnova catalog
related products
  • MK-4101

    A novel potent, orally bioavailable and brain penetrating Hedgehog pathway (Hh) inhibitor that inhibits Smoothened (Smo) with IC50 of 1.1 uM.

  • Glasdegib

    Glasdegib (PF-04449913) is a potent, orally bioavailable smoothened (SMO) inhibitor with IC50 of 5 nM in the Gli-luciferase reporter assays.

  • LY2940680

    LY2940680 (Taladegib) is potent Smoothened (SMO) receptor antagonist.