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S100P-IN-1
CAS No. 690991-06-1
S100P-IN-1( —— )
Catalog No. M35653 CAS No. 690991-06-1
S100P-IN-1 is a potent S100P inhibitor.S100P-IN-1 has anti-metastatic effects on pancreatic cancer (pancreatic) cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 150 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameS100P-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionS100P-IN-1 is a potent S100P inhibitor.S100P-IN-1 has anti-metastatic effects on pancreatic cancer (pancreatic) cells.
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DescriptionS100P-IN-1 (Compound 4) is a S100P inhibitor with an IC50 of 22.7 nM. S100P-IN-1 shows anti-metastatic effects on pancreatic cancer cells.
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In VitroS100P-IN-1 (Compound 4) blocks S100P binding to RAGE in a dose dependent manner.S100P-IN-1 (10 μM, 24 h) shows S100P-specific inhibitory effect on cell invasion, without obvious cytotoxicity..Cell Invasion Assay Cell Line:Human pancreatic cancer cell lines PanC-1 (ATCC- CRL-1469), and BxPC-3 (ATCC-CRL-1687)Concentration:10 μM Incubation Time:48 h Result:Significantly inhibited invasion to the lower chamber in BxPC-3 cells, but didn’t inhibit invasion of PanC-1 (lack S100P expression) cells.Cell Viability Assay Cell Line:BxPC-3 and Panc-1 cells Concentration:10 μM Incubation Time:24 h Result:Showed no significant effect on cell metabolic activity and cytotoxicity in either cell line.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number690991-06-1
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Formula Weight440.4
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Molecular FormulaC25H16N2O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (227.07 mM; Ultrasonic )
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SMILESO=C(O)C1=CC=CC(=C1)N2C(=O)C3C4C=5C=CC=CC5C(C=6C=CC=CC64)(N(=O)=O)C3C2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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(D-Arg1,D-Pro2,D-Trp...
(D-Arg1,D-Pro2,D-Trp7·9,Leu11)-Substance P
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KIRA6
KIRA6 is an effective inhibitor of IRE1α RNase kinase (IC50: 0.6 μM). It can trigger an apoptotic response.KIRA6 (10-1000 nM, 72 hours) strongly compromises the viability of the KIT-dependent cell line HMC-1.1 at the low nM concentration, in a manner that coincided with KIT blockade.
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20-Hydroxylucidenic ...
20-Hydroxylucidenic acid E2 is a triterpenoid compound found in Ganoderma lucidum. It exhibits significant inhibitory effects on inflammation induced by TPA . Additionally, 20-Hydroxylucidenic acid E2 can suppress the expression of EBV early antigen induced by TPA , with a IC50 of 290 mol ratio/32 pmol TPA (meaning that when the molar concentration of this compound is 290 times that of 32 pmol of TPA, it can inhibit 50% of EBV early antigen expression). Therefore, 20-Hydroxylucidenic acid E2 has potential applications in anti-inflammatory and anticancer research.
