Intermedine
CAS No. 10285-06-0
Intermedine( —— )
Catalog No. M31050 CAS No. 10285-06-0
(+)-Intermedine, a pyrrolizidine alkaloid (PA), shows remarkable cytotoxic activity against neural progenitor cells (NPCs).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameIntermedine
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NoteResearch use only, not for human use.
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Brief Description(+)-Intermedine, a pyrrolizidine alkaloid (PA), shows remarkable cytotoxic activity against neural progenitor cells (NPCs).
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Description(+)-Intermedine, a pyrrolizidine alkaloid (PA), shows remarkable cytotoxic activity against neural progenitor cells (NPCs).
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In Vitro(+)-Intermedine (1.1-30 μM; 24 hours) exhibits significant cytotoxicity at 30 μM and reduces cell viability in a concentration dependent manner in neural progenitor cells (NPCs).(+)-Intermedine showsno differentiation impairment. Cell Cytotoxicity Assay Cell Line:Neural progenitor cells (NPCs) Concentration:1.1, 3.3, 10, 30 μM Incubation Time:24 hours Result:Exhibited significant cytotoxicity at 30 μM and reduced cell viability in a concentration dependent manner.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number10285-06-0
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Formula Weight299.36
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Molecular FormulaC15H25NO5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (167.02 mM)
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Senkyunolide C
Senkyunolide C is a natural product, that can be isolated from the rhizome of Cnidium officinale.
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Epimagnolin A
Epimagnolin A is a lignan obtained from the flower buds of Magnolia fargesii, which is traditionally used in Asian medicine for treating headache and nasal congestion.?A herbal compound fargesin obtained from M. fargesii, has exerted anti-inflammatory effects in human monocytic THP-1 cells in the previous study.?it was demonstrated that epimagnolin A reduced phorbol-12-myristate-13-acetate (PMA)-induced IL-6 promoter activity and IL-6 production in human monocytic THP-1 cells.?
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