Cart
sales@molnova.com
LY2881835
CAS No. 1292290-38-0
LY2881835( —— )
Catalog No. M34327 CAS No. 1292290-38-0
LY2881835 is a potent and selective GPR40 agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 411 | In Stock |
|
| 10MG | 562 | In Stock |
|
| 25MG | 866 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameLY2881835
-
NoteResearch use only, not for human use.
-
Brief DescriptionLY2881835 is a potent and selective GPR40 agonist.
-
DescriptionLY2881835 is a potent and selective agonist of G protein-coupled receptor 40 (GPR40). LY2881835 has efficacious and durable dose-dependent reductions in glucose levels along with significant increases in insulin and GLP-1 secretion. LY2881835 has the potential for the research of type 2 diabetes mellitus. LY2881835 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetGPR
-
RecptorGPR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1292290-38-0
-
Formula Weight491.62
-
Molecular FormulaC33H33NO3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC(N1CCC2(C=3C(C=C2)=CC=CC3)CC1)C4=CC=C(COC5=CC=C([C@H](CC(O)=O)C#CC)C=C5)C=C4
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Hamdouchi C, et al. The Discovery, Preclinical, and Early Clinical Development of Potent and Selective GPR40 Agonists for the Treatment of Type 2 Diabetes Mellitus (LY2881835, LY2922083, and LY2922470). J Med Chem. 2016;59(24):10891-10916.?
molnova catalog
related products
-
MS21570
MS21570 as a GPR171 antagonist based on its ability to blockwith an?IC50?of 220 Nmthat reduces anxiety-like behavior and fear conditioning in mice.
-
Azathioprine
Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases.
-
Dihydromunduletone
Dihydromunduletone (DHM) is an adhesion G protein-coupled receptor (aGPCR) antagonist that acts as a chemical probe for the inhibition of GPR56 and GPR114/ADGRG5, which have similar tethered agonists.
