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MDH1-IN-2
CAS No. 2143463-35-6
MDH1-IN-2( —— )
Catalog No. M35631 CAS No. 2143463-35-6
MDH1-IN-2 (7c) is a potent MDH1 inhibitor with an IC50 of 2.27 μM for MDH1 and 27.47 μM for MDH2. MDH1-IN-2 has potential anticancer activity and can be used in the study of diseases related to the immune system.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 150 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameMDH1-IN-2
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NoteResearch use only, not for human use.
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Brief DescriptionMDH1-IN-2 (7c) is a potent MDH1 inhibitor with an IC50 of 2.27 μM for MDH1 and 27.47 μM for MDH2. MDH1-IN-2 has potential anticancer activity and can be used in the study of diseases related to the immune system.
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DescriptionMDH1-IN-2 (Compound 7c) is a potent and selelctive inhibitor of MDH1 with an IC50 of 2.27 μM. MDH1-IN-2 has the potential for the research of cancer diseases.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2143463-35-6
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Formula Weight427.53
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Molecular FormulaC25H33NO5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (58.48 mM; Ultrasonic )
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SMILESCOC(=O)c1ccc(OC)c(NC(=O)COc2ccc(cc2)C(C)(C)CC(C)(C)C)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Naik R, et al. Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism. J Med Chem. 2017;60(20):8631-8646.?
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