Cart
sales@molnova.com
FGFR2-IN-1
CAS No. 2677709-76-9
FGFR2-IN-1( —— )
Catalog No. M35540 CAS No. 2677709-76-9
FGFR2-IN-1 is an FGFR inhibitor that inhibits FGFR1, FGFR2, and FGFR3 with IC50s of 460, 140, and 2200 nM, respectively.FGFR2-IN-1 can be used for the study of cancers associated with FGFR2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 33 | In Stock |
|
| 5MG | 56 | In Stock |
|
| 10MG | 93 | In Stock |
|
| 25MG | 158 | In Stock |
|
| 50MG | 221 | In Stock |
|
| 100MG | 334 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameFGFR2-IN-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionFGFR2-IN-1 is an FGFR inhibitor that inhibits FGFR1, FGFR2, and FGFR3 with IC50s of 460, 140, and 2200 nM, respectively.FGFR2-IN-1 can be used for the study of cancers associated with FGFR2.
-
DescriptionFGFR2-IN-1 is a selective FGFR2 inhibitor with an IC50 of 140 nM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetFGFR
-
RecptorFGFR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2677709-76-9
-
Formula Weight357.41
-
Molecular FormulaC22H19N3O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(NC1=NNC=2C=C(C=CC12)C=3C=CC=C(OCC)C3)C=4C=CC=CC4
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Turner LD, et al. From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor. J. Med. Chem. 2021 Nov 15.
molnova catalog
related products
-
Alofanib
Alofanib is a selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect on FGF2-induced phosphorylation of FRS2a in KATO III cells (IC50 <10 nM).
-
Infigratinib
Infigratinib (NVP-BGJ398, BGJ398) is a potent, selective pan-FGFR inhibitor.
-
Dovitinib lactate
A novel, multitargeted RTK inhibitor of class III, IV, and V RTKs.
