MDH1-IN-1( —— )

Catalog No. M35534 CAS No. 2143463-31-2

MDH1-IN-1 (5i) is a potent MDH1 inhibitor with an IC50 of 6.79 μM for MDH1 and >40 μM for MDH2.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

MDH1-IN-1
Note

Research use only, not for human use.
Brief Description

MDH1-IN-1 (5i) is a potent MDH1 inhibitor with an IC50 of 6.79 μM for MDH1 and >40 μM for MDH2.
Description

MDH1-IN-1 (Compound 5i) is a potent inhibitor of MDH1 with an IC50 of 6.79 μM. MDH1-IN-1 has the potential for the research of cancer diseases.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

2143463-31-2
Formula Weight

355.43
Molecular Formula

C21H25NO4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (281.35 mM; Ultrasonic )
SMILES

CCCCCc1ccc(OCC(=O)Nc2cccc(c2)C(=O)OC)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Naik R, et al. Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism. J Med Chem. 2017;60(20):8631-8646.?

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