Home - Products - Apoptosis - NF-κB - Penehyclidine hydrochloride

Penehyclidine hydrochloride

CAS No. 151937-76-7

Penehyclidine hydrochloride( —— )

Catalog No. M35531 CAS No. 151937-76-7

Penehyclidine hydrochloride (Penequinine hydrochloride) is an M1 and M3 antagonist and activates NF-κB in lung tissue.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 69 In Stock
5MG 61 In Stock
10MG 88 In Stock
25MG 147 In Stock
50MG 212 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Penehyclidine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Penehyclidine hydrochloride (Penequinine hydrochloride) is an M1 and M3 antagonist and activates NF-κB in lung tissue.
  • Description
    Penehyclidine (Penequinine) hydrochloride, a anticholinergic agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine hydrochloride activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine hydrochloride can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    NF-κB
  • Recptor
    NF-κB | AChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    151937-76-7
  • Formula Weight
    351.91
  • Molecular Formula
    C20H30ClNO2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.OC(COC1CN2CCC1CC2)(C1CCCC1)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhi-Yuan Chen, et al. The Mechanism of Penehyclidine Hydrochloride and Its Effect on the Inflammatory Response of Lung Tissue in Rats with Chronic Obstructive Pulmonary Disease During Mechanical Ventilation. Int J Chron Obstruct Pulmon Dis. 2021 Mar 31;16:877-885.?
molnova catalog
related products
  • Sinomenine hydrochlo...

    Extracted from Sinomenium Acutum Rehderett Wilson.

  • Cynaropicrin

    Cynaropicrin, a sesquiterpene lactone found in artichoke (Cynara scolymus), has anti-hepatitis C and trypanosome activity and inhibits NF-κB activation.

  • Cyanidin-3-Sambubios...

    Cyanidin 3-sambubioside (chloride) (Standard) is the analytical standard of Cyanidin 3-sambubioside (chloride). This product is intended for research and analytical applications. Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride), a major anthocyanin, a natural colorant, and is a potent NO inhibitor. Cyanidin 3-sambubioside chloride is a H274Y mutation inhibitor, and inhibits influenza neuraminidase activity with an IC50 of 72 μM. Cyanidin 3-sambubioside chloride inhibits angiotensin-converting enzyme (ACE) activity and has antioxidant, anti-angiogenic and antiviral properties.