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D75-4590
CAS No. 384376-42-5
D75-4590( —— )
Catalog No. M35527 CAS No. 384376-42-5
D75-4590 is a β-1,6-Glucan inhibitor. As glucan is a major component of the cell wall, specifically β-1,6-Glucan, D75-4590 can fight fungal infections by inhibiting its synthetase.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 39 | In Stock |
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| 5MG | 33 | In Stock |
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| 10MG | 56 | In Stock |
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| 25MG | 124 | In Stock |
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| 50MG | 193 | In Stock |
|
| 100MG | 277 | In Stock |
|
| 200MG | 369 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameD75-4590
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NoteResearch use only, not for human use.
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Brief DescriptionD75-4590 is a β-1,6-Glucan inhibitor. As glucan is a major component of the cell wall, specifically β-1,6-Glucan, D75-4590 can fight fungal infections by inhibiting its synthetase.
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DescriptionD75-4590, a pyridobenzimidazole derivative and a β-1,6-glucan synthesis inhibitor, possesses antifungal activity.
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In VitroD75-4590 has activities against a variety of Candida species, including fluconazole-resistant strains. Most strains of C. albicans, C. tropicalis, and C. parapsilosis displayed trailing growth phenomena similar to those observed in the presence of azoles.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number384376-42-5
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Formula Weight349.47
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Molecular FormulaC21H27N5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (143.07 mM; Ultrasonic (<60°C)
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SMILESCCN(CC)CCNc1c(CC)c(C)c(C#N)c2nc3ccccc3n12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Akihiro Kitamura, et al. Discovery of a small-molecule inhibitor of {beta}-1,6-glucan synthesis. Antimicrob Agents Chemother. 2009 Feb;53(2):670-7.?
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