Cart
sales@molnova.com
NLRP3-IN-11
CAS No. 2769040-91-5
NLRP3-IN-11( —— )
Catalog No. M35514 CAS No. 2769040-91-5
NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 103 | In Stock |
|
| 10MG | 150 | In Stock |
|
| 25MG | 253 | In Stock |
|
| 50MG | 367 | In Stock |
|
| 100MG | 546 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNLRP3-IN-11
-
NoteResearch use only, not for human use.
-
Brief DescriptionNLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.
-
DescriptionNLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases.
-
In VitroNLRP3-IN-11 has biological activity with an IC50 value of <0.3 μM in human PBMC NLRP3 assay.
-
In Vivo——
-
Synonyms——
-
PathwayNF-κB
-
TargetNOD
-
RecptorNOD
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2769040-91-5
-
Formula Weight344.8
-
Molecular FormulaC17H17ClN4O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (362.53 mM; Ultrasonic )
-
SMILESN(CC(C)(C)O)C=1C2=C(C(=NN1)C3=C(O)C=C(Cl)C=C3)C=CN=C2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.HY-W048205, et al. Compounds for inhibiting NLRP3 and uses thereof. Patent. US11319319B1.
molnova catalog
related products
-
Molsidomine
Molsidomine is an orally active, long acting vasodilating drug, metabolized in the liver to the active metabolite linsidomine.
-
Z-Asp-CH2-DCB
Z-Asp-CH2-DCB is an irreversible inhibitor of broad spectrum caspase.
-
NT-0796
NT-0796 is a brain-permeable, potent, and selective inhibitor of the inflammasome NLRP3, inhibiting NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.
