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SARS-CoV-2-IN-13

CAS No. 56961-10-5

SARS-CoV-2-IN-13( —— )

Catalog No. M35489 CAS No. 56961-10-5

SARS-CoV-2-IN-13 (compound 5) is an analogue of niclosamide, displaying greater stability in human plasma and liver S9 enzymes assay.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	76	In Stock
5MG	69	In Stock
10MG	112	In Stock
25MG	226	In Stock
50MG	328	In Stock
100MG	471	In Stock
200MG	638	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

SARS-CoV-2-IN-13
Note

Research use only, not for human use.
Brief Description

SARS-CoV-2-IN-13 (compound 5) is an analogue of niclosamide, displaying greater stability in human plasma and liver S9 enzymes assay.
Description

SARS-CoV-2-IN-13 (compound 5) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.057 μM. SARS-CoV-2-IN-13 is a niclosamide analogue. SARS-CoV-2-IN-13 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

SARS-CoV
Research Area

——
Indication

——

Chemical Information

CAS Number

56961-10-5
Formula Weight

327.12
Molecular Formula

C13H8Cl2N2O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 125 mg/mL (382.12 mM)
SMILES

Oc1ccc(Cl)cc1C(=O)Nc1ccc(c(Cl)c1)[N+]([O-])=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Juang YP, et al. Design, synthesis and biological evaluations of niclosamide analogues against SARS-CoV-2. Eur J Med Chem. 2022 May 5;235:114295.?

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