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AChE/BChE/MAO-B-IN-1
CAS No. 2416910-82-0
AChE/BChE/MAO-B-IN-1( —— )
Catalog No. M35486 CAS No. 2416910-82-0
AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE, and MAO-B that crosses the blood-brain barrier, exhibiting inhibitory effects on hAChE, hBChE, and hMAO-B with IC50s of 7.31, 0.56, and 26.1 μM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 85 | In Stock |
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| 5MG | 77 | In Stock |
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| 10MG | 112 | In Stock |
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| 25MG | 220 | In Stock |
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| 50MG | 307 | In Stock |
|
| 100MG | 418 | In Stock |
|
| 200MG | 564 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAChE/BChE/MAO-B-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionAChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE, and MAO-B that crosses the blood-brain barrier, exhibiting inhibitory effects on hAChE, hBChE, and hMAO-B with IC50s of 7.31, 0.56, and 26.1 μM, respectively.
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DescriptionAChE/BChE/MAO-B-IN-1 (Compound 10) is a reversible and non-time-dependent AChE, BChE and MAO-B inhibitor with IC50 values of 7.31, 0.56 and 26.1 μM for hAChE, hBChE and hMAO-B, respectively. AChE/BChE/MAO-B-IN-1 can cross the BBB and shows neuroprotective effects without cytotoxicity.
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In VitroAChE/BChE/MAO-B-IN-1 (Compound 10) prevents amyloid β1-42 (Aβ1-42)-induced neuronal cell death.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetMAO
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RecptorMAO | AChE
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Research Area——
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Indication——
Chemical Information
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CAS Number2416910-82-0
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Formula Weight324.42
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Molecular FormulaC20H24N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESC(N1CCC(COC(NC2=CC=CC=C2)=O)CC1)C3=CC=CC=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ko?ak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 Jul 1;197:112282. ?
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