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Home - Products - Metabolic Enzyme/Protease - MAO - AChE/BChE/MAO-B-IN-1

AChE/BChE/MAO-B-IN-1

CAS No. 2416910-82-0

AChE/BChE/MAO-B-IN-1( —— )

Catalog No. M35486 CAS No. 2416910-82-0

AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE, and MAO-B that crosses the blood-brain barrier, exhibiting inhibitory effects on hAChE, hBChE, and hMAO-B with IC50s of 7.31, 0.56, and 26.1 μM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 85 In Stock
5MG 77 In Stock
10MG 112 In Stock
25MG 220 In Stock
50MG 307 In Stock
100MG 418 In Stock
200MG 564 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    AChE/BChE/MAO-B-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE, and MAO-B that crosses the blood-brain barrier, exhibiting inhibitory effects on hAChE, hBChE, and hMAO-B with IC50s of 7.31, 0.56, and 26.1 μM, respectively.
  • Description
    AChE/BChE/MAO-B-IN-1 (Compound 10) is a reversible and non-time-dependent AChE, BChE and MAO-B inhibitor with IC50 values of 7.31, 0.56 and 26.1 μM for hAChE, hBChE and hMAO-B, respectively. AChE/BChE/MAO-B-IN-1 can cross the BBB and shows neuroprotective effects without cytotoxicity.
  • In Vitro
    AChE/BChE/MAO-B-IN-1 (Compound 10) prevents amyloid β1-42 (Aβ1-42)-induced neuronal cell death.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    MAO
  • Recptor
    MAO | AChE
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2416910-82-0
  • Formula Weight
    324.42
  • Molecular Formula
    C20H24N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(N1CCC(COC(NC2=CC=CC=C2)=O)CC1)C3=CC=CC=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ko?ak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 Jul 1;197:112282. ?
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