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FBA-IN-1
CAS No. 2605897-57-0
FBA-IN-1( —— )
Catalog No. M35457 CAS No. 2605897-57-0
FBA-IN-1 (compound 2a11) is a first-in-class, covalent, and allosteric inhibitor of fructose-1,6-bisphosphate aldolase (FBA) from Candida albicans (CaFBA).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 226 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameFBA-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionFBA-IN-1 (compound 2a11) is a first-in-class, covalent, and allosteric inhibitor of fructose-1,6-bisphosphate aldolase (FBA) from Candida albicans (CaFBA).
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DescriptionFBA-IN-1 (compound 2a11) is a first-in-class, covalent and allosteric inhibitor of fructose-1,6-bisphosphate aldolase from Candida albicans (CaFBA). FBA-IN-1 inhibits the growth of Azole-resistant strains 103 with the MIC80 of 1 μg/mL.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetAntifungal
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RecptorAntifungal
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Research Area——
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Indication——
Chemical Information
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CAS Number2605897-57-0
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Formula Weight302.23
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Molecular FormulaC15H13NOSe
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (330.87 mM; Ultrasonic )
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SMILESO=C1C=2C=CC=CC2[Se]N1C3=CC=C(C=C3)CC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wuqiang Wen, et al. Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of Candidiasis. J Med Chem. 2022 Feb 10;65(3):2656-2674.?
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