Columbianetin is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage it also has antifungal activity. Columbianetin has anti-inflammatory effects it promotes histamine release and inhibits the histamine release by substance P suggests that it may be helpful in regulating mast cell-mediated allergic inflammatory responses. (2'S)-columbianetin can be effectively used to protect keratinocytes from UVB induced damage.

ME1111, a succinate dehydrogenase inhibitor of Trichophyton species, serves as an antifungal agent effective against dermatophytes.

ACHE-IN-38 is a potent Acetylcholinesterase inhibitor that can be used for the synthesis of compounds with anti-inflammatory, anti-tumor, and antibacterial activities.