DHODH-IN-17( —— )

Catalog No. M35407 CAS No. 16344-26-6

DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM. DHODH-IN-17 is a 2- anilino nicotinic acid that can be used in the study of acute myeloid leukemia (AML).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	39	In Stock
5MG	36	In Stock
10MG	60	In Stock
25MG	122	In Stock
50MG	178	In Stock
100MG	263	In Stock
200MG	368	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

DHODH-IN-17
Note

Research use only, not for human use.
Brief Description

DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM. DHODH-IN-17 is a 2- anilino nicotinic acid that can be used in the study of acute myeloid leukemia (AML).
Description

DHODH-IN-17, a 2-anilino nicotinic acid, is a human DHODH inhibitor (IC50=0.40 μM). DHODH-IN-17 can be used for theresearch of acute myeloid leukemia (AML).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Dehydrogenase
Recptor

Dehydrogenase
Research Area

——
Indication

——

Chemical Information

CAS Number

16344-26-6
Formula Weight

248.67
Molecular Formula

C12H9ClN2O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 83.33 mg/mL (335.10 mM; Ultrasonic )
SMILES

OC(=O)C1=C(NC2=CC=C(Cl)C=C2)N=CC=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Lewis TA, et al. Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. ACS Med Chem Lett. 2016;7(12):1112-1117.

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