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MitoBloCK-6
CAS No. 303215-67-0
MitoBloCK-6( —— )
Catalog No. M35338 CAS No. 303215-67-0
MitoBloCK-6 is a potent Erv1/ALR inhibitor with IC50 values of 900 nM and 700 nM, respectively, and also inhibits Erv2 with an IC50 of 1.4 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 31 | In Stock |
|
| 10MG | 45 | In Stock |
|
| 25MG | 72 | In Stock |
|
| 50MG | 117 | In Stock |
|
| 100MG | 183 | In Stock |
|
| 200MG | 276 | In Stock |
|
| 500MG | 480 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMitoBloCK-6
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NoteResearch use only, not for human use.
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Brief DescriptionMitoBloCK-6 is a potent Erv1/ALR inhibitor with IC50 values of 900 nM and 700 nM, respectively, and also inhibits Erv2 with an IC50 of 1.4 μM.
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DescriptionMitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 (IC50=1.4 μM). MitoBloCK-6 can induce apoptosis via cytochrome c release in hESCs.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number303215-67-0
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Formula Weight357.23
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Molecular FormulaC19H14Cl2N2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (139.97 mM)
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SMILESOc1c(Cl)cc(Cl)cc1\C=N\c1ccc(Nc2ccccc2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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KT5823
KT5823 is a selective and potent cGMP-dependent protein kinase (PKG) inhibitor with inhibitory effects on PKA and PKC.KT5823 increases thyroid-stimulating hormone-induced (Na+/I- symporter) NIS expression and iodide ion uptake by modulating sodium iodide symporter protein expression and activity in thyroid cells. KT5823 induces apoptosis.
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GSK-3β inhibitor 3
GSK-3β inhibitor 3 is a potent, selective, and irreversible covalent inhibitor of glycogen synthase kinase 3β (GSK-3β) with an IC50 of 6.6 μM, and can be used to study acute promyelocytic leukemia.
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MY-1076
MY-1076 is a potent YAP inhibitor with antigastric cancer activity.MY-1076 dose-dependently induced G2/M phase block, induced YAP degradation and apoptosis, and inhibited microtubule protein polymerization.
