Home - Products - Apoptosis - Apoptosis - MitoBloCK-6

MitoBloCK-6

CAS No. 303215-67-0

MitoBloCK-6( —— )

Catalog No. M35338 CAS No. 303215-67-0

MitoBloCK-6 is a potent Erv1/ALR inhibitor with IC50 values of 900 nM and 700 nM, respectively, and also inhibits Erv2 with an IC50 of 1.4 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	31	In Stock
10MG	45	In Stock
25MG	72	In Stock
50MG	117	In Stock
100MG	183	In Stock
200MG	276	In Stock
500MG	480	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

MitoBloCK-6
Note

Research use only, not for human use.
Brief Description

MitoBloCK-6 is a potent Erv1/ALR inhibitor with IC50 values of 900 nM and 700 nM, respectively, and also inhibits Erv2 with an IC50 of 1.4 μM.
Description

MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 (IC50=1.4 μM). MitoBloCK-6 can induce apoptosis via cytochrome c release in hESCs.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

Apoptosis
Recptor

Apoptosis
Research Area

——
Indication

——

Chemical Information

CAS Number

303215-67-0
Formula Weight

357.23
Molecular Formula

C19H14Cl2N2O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (139.97 mM)
SMILES

Oc1c(Cl)cc(Cl)cc1\C=N\c1ccc(Nc2ccccc2)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Dabir DV, et, al. A small molecule inhibitor of redox-regulated protein translocation into mitochondria. Dev Cell. 2013 Apr 15;25(1):81-92. ?

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Isatuximab

Isatuximab is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38 in malignant cells of the hematological system, a highly expressed protein in multiple myeloma.
Pipobroman

Pipobroman is an anti-cancer drug that probably acts as an alkylating agent.
β-Elemene

β-Elemene is a natural product isolated from Curcuma wenyujin, with an antitumor activity and induce cell apoptosis.β-Elemene significantly inhibited the metastatic capacity of MDR gastric cells in vivo and in vitro.?Mechanistically, β-Elemene regulated MMP-2/9 expression and reversed epithelial-mesenchymal transition.?

Sign In Join Free