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MitoBloCK-6

CAS No. 303215-67-0

MitoBloCK-6( —— )

Catalog No. M35338 CAS No. 303215-67-0

MitoBloCK-6 is a potent Erv1/ALR inhibitor with IC50 values of 900 nM and 700 nM, respectively, and also inhibits Erv2 with an IC50 of 1.4 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
5MG	31	Get Quote
10MG	45	Get Quote
25MG	70	Get Quote
50MG	116	Get Quote
100MG	177	Get Quote
200MG	267	Get Quote
500MG	464	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

MitoBloCK-6
Note

Research use only, not for human use.
Brief Description

MitoBloCK-6 is a potent Erv1/ALR inhibitor with IC50 values of 900 nM and 700 nM, respectively, and also inhibits Erv2 with an IC50 of 1.4 μM.
Description

MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 (IC50=1.4 μM). MitoBloCK-6 can induce apoptosis via cytochrome c release in hESCs.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

Apoptosis
Recptor

Apoptosis
Research Area

——
Indication

——

Chemical Information

CAS Number

303215-67-0
Formula Weight

357.23
Molecular Formula

C19H14Cl2N2O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (139.97 mM)
SMILES

Oc1c(Cl)cc(Cl)cc1\C=N\c1ccc(Nc2ccccc2)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Dabir DV, et, al. A small molecule inhibitor of redox-regulated protein translocation into mitochondria. Dev Cell. 2013 Apr 15;25(1):81-92. ?

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