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FEN1-IN-2

CAS No. 824983-94-0

FEN1-IN-2( —— )

Catalog No. M35240 CAS No. 824983-94-0

FEN1-IN-2 is a selective and potent inhibitor of flap endonuclease 1 (FEN1), inhibits FEN1 and XPG, has potential anticancer activity, and can be used to study DNA damage repair.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 164 In Stock
2MG 90 In Stock
5MG 148 In Stock
10MG 235 In Stock
25MG 471 In Stock
50MG 732 In Stock
100MG 1144 In Stock
200MG Get Quote In Stock
500MG 2306 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    FEN1-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    FEN1-IN-2 is a selective and potent inhibitor of flap endonuclease 1 (FEN1), inhibits FEN1 and XPG, has potential anticancer activity, and can be used to study DNA damage repair.
  • Description
    FEN1-IN-2 (compound 20) is a flap endonuclease 1 (FEN1) inhibitor, with IC50 values of 3 nM and 226 nM for FEN1 and XPG, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    824983-94-0
  • Formula Weight
    393.42
  • Molecular Formula
    C20H15N3O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (254.18 mM; Ultrasonic )
  • SMILES
    O=C(N)C1=CC=C(C=C1)C=2C=CC=C(C2)CN3C(=O)N(O)C(=O)C=4SC=CC43
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. L Nathan Tumey, et al. The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors. Bioorg Med Chem Lett. 2005 Jan 17;15(2):277-81.?
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