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Simpinicline
CAS No. 753015-44-0
Simpinicline( —— )
Catalog No. M35236 CAS No. 753015-44-0
Simpinicline (OC-02) (OC-02) is a highly selective nicotinic acetylcholine receptor (nAChR) agonist that activates the trigeminal parasympathetic pathway and can be used to treat dry eye.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 922 | In Stock |
|
| 10MG | 1226 | In Stock |
|
| 25MG | 1853 | In Stock |
|
| 50MG | 2437 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSimpinicline
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NoteResearch use only, not for human use.
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Brief DescriptionSimpinicline (OC-02) (OC-02) is a highly selective nicotinic acetylcholine receptor (nAChR) agonist that activates the trigeminal parasympathetic pathway and can be used to treat dry eye.
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DescriptionSimpinicline (OC-02), a highly selective nicotinic acetylcholine receptor (nAChR) agonist, shows potent antiviral activity against the SARS-CoV-2 variants in cell culture with an IC50 of 0.04 μM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetAChE
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RecptorAChE | AChR
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Research Area——
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Indication——
Chemical Information
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CAS Number753015-44-0
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Formula Weight175.23
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Molecular FormulaC10H13N3
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Purity>98% (HPLC)
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Solubility——
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SMILESC(=C/[C@H]1CCNC1)\C=2C=NC=NC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Quik M, et al. α4β2 Nicotinic receptors play a role in the nAChR-mediated decline in L-dopa-induced dyskinesias in parkinsonian rats. Neuropharmacology. 2013 Aug;71:191-203.?
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