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Simpinicline

CAS No. 753015-44-0

Simpinicline( —— )

Catalog No. M35236 CAS No. 753015-44-0

Simpinicline (OC-02) (OC-02) is a highly selective nicotinic acetylcholine receptor (nAChR) agonist that activates the trigeminal parasympathetic pathway and can be used to treat dry eye.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Simpinicline
  • Note
    Research use only, not for human use.
  • Brief Description
    Simpinicline (OC-02) (OC-02) is a highly selective nicotinic acetylcholine receptor (nAChR) agonist that activates the trigeminal parasympathetic pathway and can be used to treat dry eye.
  • Description
    Simpinicline (OC-02), a highly selective nicotinic acetylcholine receptor (nAChR) agonist, shows potent antiviral activity against the SARS-CoV-2 variants in cell culture with an IC50 of 0.04 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    AChE
  • Recptor
    AChE | AChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    753015-44-0
  • Formula Weight
    175.23
  • Molecular Formula
    C10H13N3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(=C/[C@H]1CCNC1)\C=2C=NC=NC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Quik M, et al. α4β2 Nicotinic receptors play a role in the nAChR-mediated decline in L-dopa-induced dyskinesias in parkinsonian rats. Neuropharmacology. 2013 Aug;71:191-203.?
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