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γ-Acetylenic GABA hydrochloride

CAS No. 103451-26-9

γ-Acetylenic GABA hydrochloride( —— )

Catalog No. M35222 CAS No. 103451-26-9

γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 51 In Stock
5MG 48 In Stock
10MG 71 In Stock
25MG 122 In Stock
50MG 179 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    γ-Acetylenic GABA hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.
  • Description
    γ-Acetylenic GABA (GAG) hydrochloride is an irreversible inhibitor of GABA-transaminase. γ-Acetylenic GABA hydrochloride can increase the concentration of GABA in rat brain. γ-Acetylenic GABA (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • In Vitro
    ——
  • In Vivo
    γ-Acetylenic GABA hydrochloride (100 mg/kg i.p.) inhibits GABA-transaminase activity and causes a several-fold increase in the concentration of GABA in rat brain.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Transaminase | GABA Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    103451-26-9
  • Formula Weight
    163.6
  • Molecular Formula
    C6H10ClNO2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.O=C(O)CCC(C#C)N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Casey DE, et, al. gamma-Acetylenic GABA in tardive dyskinesia. Arch Gen Psychiatry. 1980 Dec;37(12):1376-9.?
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