Cart
sales@molnova.com
HPK1-IN-4
CAS No. 2739844-28-9
HPK1-IN-4( —— )
Catalog No. M35202 CAS No. 2739844-28-9
HPK1-IN-4 is an HPK1 (MAPK41) inhibitor with an IC 50 of 0.061 nM. HPK1-IN-4 is often used as a preclinical immunotherapy tool compound.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 345 | In Stock |
|
| 5MG | 312 | In Stock |
|
| 10MG | 471 | In Stock |
|
| 25MG | 825 | In Stock |
|
| 50MG | 1107 | In Stock |
|
| 100MG | 1516 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameHPK1-IN-4
-
NoteResearch use only, not for human use.
-
Brief DescriptionHPK1-IN-4 is an HPK1 (MAPK41) inhibitor with an IC 50 of 0.061 nM. HPK1-IN-4 is often used as a preclinical immunotherapy tool compound.
-
DescriptionHPK1-IN-4 (comp 22) is a HPK1 (MAPK41) inhibitor (IC50 of 0.061 nM) as preclinical immunoresearch tool compound.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMAPK/ERK Signaling
-
Targetp38 MAPK
-
RecptorMAPK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2739844-28-9
-
Formula Weight434.49
-
Molecular FormulaC23H26N6O3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (230.15 mM; ultrasonic and adjust pH to 4 with HCl )
-
SMILESCOc1cc2CCN(C)Cc2cc1Nc1ncc(C(N)=O)c(Nc2ccccc2CO)n1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Brandon A Vara, et al. Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds. ACS Med Chem Lett. 2021 Mar 19;12(4):653-661.?
molnova catalog
related products
-
RWJ 67657
A potent, selective, orally active p38 MAPK inhibitor that inhibits the production of TNF-α and IL-1β by LPS-stimulated human PBMCs with IC50 of 3 and 11 nM, respectively.
-
DAMGO
DAMGO is an opioid receptor agonist with the ability to affect the locomotive activity in rodents. Possible analgesic agent due to μ-opiod receptor interaction.
-
R1487
R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.
