Cart
sales@molnova.com
Home - Products - Others - Other Targets - α-Conotoxin MI

α-Conotoxin MI

CAS No. 88217-10-1

α-Conotoxin MI( ——— )

Catalog No. M41036 CAS No. 88217-10-1

α-Conotoxin M I is a potent and selective inhibitor of mAChR and α1β1γδ nAChR, but has no effect on nicotine-stimulated dopamine release. α-Conotoxins are small, disulfide-rich peptides that competitively inhibit muscle and neuronal nicotinic AChRs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG Get Quote Get Quote
50MG Get Quote Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    α-Conotoxin MI
  • Note
    Research use only, not for human use.
  • Brief Description
    α-Conotoxin M I is a potent and selective inhibitor of mAChR and α1β1γδ nAChR, but has no effect on nicotine-stimulated dopamine release. α-Conotoxins are small, disulfide-rich peptides that competitively inhibit muscle and neuronal nicotinic AChRs.
  • Description
    α-Conotoxin M I is a potent and selective inhibitor of mAChR and α1β1γδ nAChR, but has no effect on nicotine-stimulated dopamine release. α-Conotoxins are small, disulfide-rich peptides that competitively inhibit muscle and neuronal nicotinic AChRs.
  • In Vitro
    α-Conotoxin M I interacts with the α-δ site of the AChR through four hydrophobic residues in its N- and C-terminal loops. Furthermore, the key side chains in α-Conotoxin M I localize in a hydrophobic cluster that interacts with hydrophobic and aromatic residues from both the a and d subunits.
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    mAChR; α1β1γδ nAChR
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    88217-10-1
  • Formula Weight
    1497.74
  • Molecular Formula
    C58H92N22O17S4
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kulak JM, et al. Alpha-conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes. J Neurosci. 1997 Jul 15;17(14):5263-70. ?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Morin Hydrate

    Morin hydrate(Aurantica) is a flavonoid isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).

  • Cytochalasin H

    Cytochalasin H is a potent inhibitor of actin incorporation into filaments.

  • Linolenic acid ethyl...

    Ethyl linolenate (Standard) is the analytical standard of Ethyl linolenate. This product is intended for research and analytical applications. Ethyl linolenate is a fatty acid ethyl ester (FAEE). Ethyl linolenate plays an active role in inhibition of the cellular production on melanin with an IC50 of 70 μM. Anti-melanogenesis Effects.

Sign In Join Free