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Azide-PEG3-Desthiobiotin
CAS No. 1426828-06-9
Azide-PEG3-Desthiobiotin( —— )
Catalog No. M35075 CAS No. 1426828-06-9
Azide-PEG3-Desthiobiotin is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 68 | In Stock |
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| 10MG | 116 | In Stock |
|
| 25MG | 258 | In Stock |
|
| 50MG | 407 | In Stock |
|
| 100MG | 612 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1283 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAzide-PEG3-Desthiobiotin
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NoteResearch use only, not for human use.
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Brief DescriptionAzide-PEG3-Desthiobiotin is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
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DescriptionAzide-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azide-PEG3-Desthiobiotin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1426828-06-9
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Formula Weight414.5
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Molecular FormulaC18H34N6O5
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Purity>98% (HPLC)
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Solubility——
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SMILESC(CCCCC(NCCOCCOCCOCCN=[N+]=[N-])=O)[C@@H]1[C@H](C)NC(=O)N1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
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