Cotosudil
CAS No. 1258833-31-6
Cotosudil( —— )
Catalog No. M35056 CAS No. 1258833-31-6
Cotosudil is a ROCK kinase inhibitor with antihypertensive activity and is used to treat or prevent diseases or conditions caused by cataracts, cardiovascular or neurodegenerative diseases or nerve damage.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 274 | In Stock |
|
| 5MG | 250 | In Stock |
|
| 10MG | 376 | In Stock |
|
| 25MG | 645 | In Stock |
|
| 50MG | 892 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCotosudil
-
NoteResearch use only, not for human use.
-
Brief DescriptionCotosudil is a ROCK kinase inhibitor with antihypertensive activity and is used to treat or prevent diseases or conditions caused by cataracts, cardiovascular or neurodegenerative diseases or nerve damage.
-
DescriptionCotosudil is a ROCK kinase inhibitor, which can be used for glaucoma or ocular hypertension research.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetROCK
-
RecptorROCK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1258833-31-6
-
Formula Weight319.42
-
Molecular FormulaC16H21N3O2S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (156.53 mM; Ultrasonic (<60°C)
-
SMILESC[C@@H]1CNCCCCN1S(=O)(=O)c1ccc2cnccc2c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. IYoshihiro Inoue, et al. Prophylactic or therapeutic agent for glaucoma or ocular hypertension. JP2013035802A.
molnova catalog
related products
-
SAR407899 hydrochlor...
SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively.
-
Rhodblock 6
Rhodblock 6 is a Rho kinase (ROCK) inhibitor that specifically inhibits Rho kinase activity and the localization of phosphorylated MRLC (Myosin Regulatory Light Chain).
-
Narciclasine
Narciclasine, a natural product, modulates the Rho/Rho-kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity.
Cart
sales@molnova.com