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(Rac)-Z-Phe-Phe-FMK
CAS No. 108005-94-3
(Rac)-Z-Phe-Phe-FMK( —— )
Catalog No. M35042 CAS No. 108005-94-3
(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 302 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Name(Rac)-Z-Phe-Phe-FMK
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NoteResearch use only, not for human use.
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Brief Description(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .
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DescriptionCathepsin L-IN-2 (Z-Phe-Phe-FMK) is a potent and irreversible cathepsin L and cathepsin B inhibitor.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetCysteine Protease
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RecptorCysteine Protease | Beta Amyloid
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Research Area——
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Indication——
Chemical Information
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CAS Number108005-94-3
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Formula Weight462.51
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Molecular FormulaC27H27FN2O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 42.5 mg/mL (91.89 mM; Ultrasonic )
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SMILESO=C(OCC=1C=CC=CC1)NC(C(=O)NC(C(=O)CF)CC=2C=CC=CC2)CC=3C=CC=CC3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jonathan Frew, et al. Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency. Mol Neurodegener. 2020 Mar 16;15(1):21.?
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