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RMC-0331
CAS No. 2488788-52-7
RMC-0331( —— )
Catalog No. M35014 CAS No. 2488788-52-7
RMC-0331 (RM-023) is an orally available and potent SOS1 inhibitor with potential anticancer activity, blocking RAS activation by disrupting RAS-SOS1 interactions.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 225 | Get Quote |
|
| 5MG | 353 | Get Quote |
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| 10MG | 630 | Get Quote |
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| 25MG | 1260 | Get Quote |
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| 50MG | 1950 | Get Quote |
|
| 100MG | 2844 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameRMC-0331
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NoteResearch use only, not for human use.
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Brief DescriptionRMC-0331 (RM-023) is an orally available and potent SOS1 inhibitor with potential anticancer activity, blocking RAS activation by disrupting RAS-SOS1 interactions.
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DescriptionRMC-0331 (RM-023) is a potent, selective and orally bioavailable SOS1 inhibitor. RMC-0331 is an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMAPK/ERK Signaling
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TargetRaf
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RecptorRaf
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Research Area——
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Indication——
Chemical Information
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CAS Number2488788-52-7
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Formula Weight499.91
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Molecular FormulaC22H25ClF3N5O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (250.05 mM; Ultrasonic )
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SMILESCOC1(CCOCC1)C(=O)N1Cc2nc(Cl)nc(N[C@H](C)c3cc(N)cc(c3)C(F)(F)F)c2C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Andreas Buckl, et al. Discovery of a Potent, Selective and Orally Bioavailable SOS1 Inhibitor, RMC-0331 (RM-023), an in vivo Tool Compound that Blocks RAS Activation via Disruption of the RAS-SOS1 Interaction.
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