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N-Desmethyl Pimavanserin
CAS No. 639863-77-7
N-Desmethyl Pimavanserin( —— )
Catalog No. M34992 CAS No. 639863-77-7
N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin, a 5-HT2A receptor inverse agonist, which is used in the treatment of sleep disorders such as insomnia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 97 | Get Quote |
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| 5MG | 264 | Get Quote |
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| 10MG | 377 | Get Quote |
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| 25MG | 615 | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameN-Desmethyl Pimavanserin
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NoteResearch use only, not for human use.
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Brief DescriptionN-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin, a 5-HT2A receptor inverse agonist, which is used in the treatment of sleep disorders such as insomnia.
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DescriptionN-Desmethyl Pimavanserin is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.
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In VitroThe mean plasma half-lives for Pimavanserin and its metabolite N-Desmethyl Pimavanserin (AC-279) are 57 hours and 200 hours, respectively.
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number639863-77-7
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Formula Weight413.53
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Molecular FormulaC24H32FN3O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (302.28 mM; Ultrasonic (<60°C)
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SMILESCC(C)COc1ccc(CNC(=O)N(Cc2ccc(F)cc2)C2CCNCC2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Vanover KE, et al. Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inver?
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