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bPiDDB
CAS No. 525596-66-1
bPiDDB( —— )
Catalog No. M34983 CAS No. 525596-66-1
bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 64 | In Stock |
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| 2MG | 34 | In Stock |
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| 5MG | 52 | In Stock |
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| 10MG | 92 | In Stock |
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| 25MG | 188 | In Stock |
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| 50MG | 272 | In Stock |
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| 100MG | 403 | In Stock |
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| 200MG | 593 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamebPiDDB
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NoteResearch use only, not for human use.
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Brief DescriptionbPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.
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DescriptionbPiDDB is a potent nAChR antagonist. bPiDDB potently (IC50=2 nM) inhibits nicotine-evoked striatal dopamine (DA) release through an interaction with α6β2-containing nAChRs.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetAChR
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RecptorAChR
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Research Area——
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Indication——
Chemical Information
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CAS Number525596-66-1
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Formula Weight514.38
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Molecular FormulaC24H38Br2N2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (194.41 mM; Ultrasonic )
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SMILES[Br-].[Br-].Cc1ccc[n+](CCCCCCCCCCCC[n+]2cccc(C)c2)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Smith AM, et al. Repeated nicotine administration robustly increases bPiDDB inhibitory potency at alpha6beta2-containing nicotinic receptors mediating nicotine-evoked dopamine release. Biochem Pharmacol. 2010 Aug 1;80(3):402-9. ?
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