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bPiDDB

CAS No. 525596-66-1

bPiDDB( —— )

Catalog No. M34983 CAS No. 525596-66-1

bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 64 In Stock
2MG 34 In Stock
5MG 52 In Stock
10MG 92 In Stock
25MG 188 In Stock
50MG 272 In Stock
100MG 403 In Stock
200MG 593 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    bPiDDB
  • Note
    Research use only, not for human use.
  • Brief Description
    bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.
  • Description
    bPiDDB is a potent nAChR antagonist. bPiDDB potently (IC50=2 nM) inhibits nicotine-evoked striatal dopamine (DA) release through an interaction with α6β2-containing nAChRs.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    AChR
  • Recptor
    AChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    525596-66-1
  • Formula Weight
    514.38
  • Molecular Formula
    C24H38Br2N2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (194.41 mM; Ultrasonic )
  • SMILES
    [Br-].[Br-].Cc1ccc[n+](CCCCCCCCCCCC[n+]2cccc(C)c2)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Smith AM, et al. Repeated nicotine administration robustly increases bPiDDB inhibitory potency at alpha6beta2-containing nicotinic receptors mediating nicotine-evoked dopamine release. Biochem Pharmacol. 2010 Aug 1;80(3):402-9. ?
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