bPiDDB( —— )

Catalog No. M34983 CAS No. 525596-66-1

bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	64	In Stock
2MG	34	In Stock
5MG	52	In Stock
10MG	92	In Stock
25MG	188	In Stock
50MG	272	In Stock
100MG	403	In Stock
200MG	593	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

bPiDDB
Note

Research use only, not for human use.
Brief Description

bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.
Description

bPiDDB is a potent nAChR antagonist. bPiDDB potently (IC50=2 nM) inhibits nicotine-evoked striatal dopamine (DA) release through an interaction with α6β2-containing nAChRs.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

AChR
Recptor

AChR
Research Area

——
Indication

——

Chemical Information

CAS Number

525596-66-1
Formula Weight

514.38
Molecular Formula

C24H38Br2N2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (194.41 mM; Ultrasonic )
SMILES

[Br-].[Br-].Cc1ccc[n+](CCCCCCCCCCCC[n+]2cccc(C)c2)c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Smith AM, et al. Repeated nicotine administration robustly increases bPiDDB inhibitory potency at alpha6beta2-containing nicotinic receptors mediating nicotine-evoked dopamine release. Biochem Pharmacol. 2010 Aug 1;80(3):402-9. ?

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