Cart
sales@molnova.com
bPiDDB
CAS No. 525596-66-1
bPiDDB( —— )
Catalog No. M34983 CAS No. 525596-66-1
bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 64 | In Stock |
|
| 2MG | 34 | In Stock |
|
| 5MG | 52 | In Stock |
|
| 10MG | 92 | In Stock |
|
| 25MG | 188 | In Stock |
|
| 50MG | 272 | In Stock |
|
| 100MG | 403 | In Stock |
|
| 200MG | 593 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamebPiDDB
-
NoteResearch use only, not for human use.
-
Brief DescriptionbPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.
-
DescriptionbPiDDB is a potent nAChR antagonist. bPiDDB potently (IC50=2 nM) inhibits nicotine-evoked striatal dopamine (DA) release through an interaction with α6β2-containing nAChRs.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetAChR
-
RecptorAChR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number525596-66-1
-
Formula Weight514.38
-
Molecular FormulaC24H38Br2N2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (194.41 mM; Ultrasonic )
-
SMILES[Br-].[Br-].Cc1ccc[n+](CCCCCCCCCCCC[n+]2cccc(C)c2)c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Smith AM, et al. Repeated nicotine administration robustly increases bPiDDB inhibitory potency at alpha6beta2-containing nicotinic receptors mediating nicotine-evoked dopamine release. Biochem Pharmacol. 2010 Aug 1;80(3):402-9. ?
molnova catalog
related products
-
SCH-900271
SCH-900271 is a potent nicotinic acid receptor for the treatment of dyslipidaemia and is commonly used in the study of mixed hyperlipidaemia and primary hypercholesterolaemia.
-
PNU-282987 free base
PNU-282987 (free base) is a potent agonist of α7 nicotinic acetylcholine receptor (nAChR) with an EC50 of 154 nM and a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM.
-
Ticarcillin sodium
Ticarcillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria.
