GIP (3-42), human
CAS No. 1802086-25-4
GIP (3-42), human( —— )
Catalog No. M34964 CAS No. 1802086-25-4
GIP (3-42), human (Gastric Inhibitory Polypeptide (3-42) (human)) is a peptide that acts as a glucose-dependent proinsulinotropic polypeptide (GIP) receptor antagonist and regulates insulin secretion and the metabolic effects of GIP in vivo, which can be used to study type 2 diabetes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 463 | In Stock |
|
| 10MG | 661 | In Stock |
|
| 25MG | 1036 | In Stock |
|
| 50MG | 1386 | In Stock |
|
| 100MG | 1841 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGIP (3-42), human
-
NoteResearch use only, not for human use.
-
Brief DescriptionGIP (3-42), human (Gastric Inhibitory Polypeptide (3-42) (human)) is a peptide that acts as a glucose-dependent proinsulinotropic polypeptide (GIP) receptor antagonist and regulates insulin secretion and the metabolic effects of GIP in vivo, which can be used to study type 2 diabetes.
-
DescriptionGIP (3-42), human acts as a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist, moderating the insulin secreting and metabolic actions of GIP in vivo.
-
In VitroThe incretin hormone GIP is rapidly degraded in the circulation by dipeptidyl peptidase IV (DPP IV) forming the N-terminally truncated peptide GIP(3-42).
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetIGF-1R
-
RecptorIGF-1R
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1802086-25-4
-
Formula Weight4749.35
-
Molecular FormulaC214H324N58O63S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (21.06 mM; Ultrasonic )H2O : 50 mg/mL (10.53 mM; Ultrasonic)
-
SMILES——
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. V A Gault, et al. Evidence that the major degradation product of glucose-dependent insulinotropic polypeptide, GIP(3-42), is a GIP receptor antagonist in vivo. J Endocrinol. 2002 Nov;175(2):525-33.?
molnova catalog
related products
-
IGF-I 24-41
IGF-I (24-41) is a 24-41 amino acid fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions).
-
NBI-31772
NBI-31772 is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki = 47 nM). NBI-31772 can be used in research on IGF-responsive diseases.
-
PQ401 hydrochloride
PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM.
Cart
sales@molnova.com