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Xanomeline
CAS No. 131986-45-3
Xanomeline( —— )
Catalog No. M34867 CAS No. 131986-45-3
Xanomeline (LY-246708) is a functionally selective M1/M4 activator used in the study of neurological disorders such as schizophrenia and has shown promising treatment in preclinical trials.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 50 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 77 | In Stock |
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| 25MG | 155 | In Stock |
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| 50MG | 245 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameXanomeline
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NoteResearch use only, not for human use.
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Brief DescriptionXanomeline (LY-246708) is a functionally selective M1/M4 activator used in the study of neurological disorders such as schizophrenia and has shown promising treatment in preclinical trials.
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DescriptionXanomeline, as an effective and selective muscarinic type 1 and type 4 (M1/M4) receptor agonist, increases neuronal excitability. Xanomeline can be used for the research of neurological disorders, such as schizophrenia.
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In Vitro——
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In VivoAnimal Model:Male Cebus apella monkeys Dosage:0.5~3 mg/kg Administration:S.c.; 1~3 hours Result:Induced salivation and vomiting in some monkeys.
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetAChR
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RecptorAChR
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Research Area——
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Indication——
Chemical Information
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CAS Number131986-45-3
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Formula Weight281.42
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Molecular FormulaC14H23N3OS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 33.33 mg/mL (118.44 mM; Ultrasonic )
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SMILESCCCCCCOc1nsnc1C1=CCCN(C)C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kreir M, et al. Role of Kv7.2/Kv7.3 and M1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons. Eur J Pharmacol. 2019;858:172474?
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