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Xanomeline

CAS No. 131986-45-3

Xanomeline( —— )

Catalog No. M34867 CAS No. 131986-45-3

Xanomeline (LY-246708) is a functionally selective M1/M4 activator used in the study of neurological disorders such as schizophrenia and has shown promising treatment in preclinical trials.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 48 In Stock
10MG 91 In Stock
25MG 155 In Stock
50MG 274 In Stock
100MG 440 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Xanomeline
  • Note
    Research use only, not for human use.
  • Brief Description
    Xanomeline (LY-246708) is a functionally selective M1/M4 activator used in the study of neurological disorders such as schizophrenia and has shown promising treatment in preclinical trials.
  • Description
    Xanomeline, as an effective and selective muscarinic type 1 and type 4 (M1/M4) receptor agonist, increases neuronal excitability. Xanomeline can be used for the research of neurological disorders, such as schizophrenia.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Cebus apella monkeys Dosage:0.5~3 mg/kg Administration:S.c.; 1~3 hours Result:Induced salivation and vomiting in some monkeys.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    AChR
  • Recptor
    AChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    131986-45-3
  • Formula Weight
    281.42
  • Molecular Formula
    C14H23N3OS
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 33.33 mg/mL (118.44 mM; Ultrasonic )
  • SMILES
    CCCCCCOc1nsnc1C1=CCCN(C)C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kreir M, et al. Role of Kv7.2/Kv7.3 and M1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons. Eur J Pharmacol. 2019;858:172474?
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