Cart
sales@molnova.com
Home - Products - GPCR/G Protein - Prostaglandin Receptor - Aligeron

Aligeron

CAS No. 70713-45-0

Aligeron( —— )

Catalog No. M34866 CAS No. 70713-45-0

Aligeron, a non-selective prostaglandin (PG) antagonist, inhibits PGF2α- and PGE2-induced blood pressure decreases in cats and can prevent PGF2α-induced diarrhea in mice and PGE2-induced paw edema in rats.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 1710 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Aligeron
  • Note
    Research use only, not for human use.
  • Brief Description
    Aligeron, a non-selective prostaglandin (PG) antagonist, inhibits PGF2α- and PGE2-induced blood pressure decreases in cats and can prevent PGF2α-induced diarrhea in mice and PGE2-induced paw edema in rats.
  • Description
    Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.
  • In Vitro
    Aligeron shows a broad spectrum of antagonistic action against different spasmogens in different isolated organs. The experiments on isolated perfused rabbit artery shows the antagonistic action of aligeron against the vasoconstrictor effects of noradrenaline and adrenaline.
  • In Vivo
    In hypoventilation hypoxia, aligeron (5 mg/kg i.v.) and cinnarizine increase cortical resistance to hypoxia and accelerated the recovery of cortical bioelectrical activity. In KCl- and AMP-induced depressions aligeron shows a protective effect manifested in a decrease of the degree and duration of the depression.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Prostaglandin Receptor
  • Recptor
    Prostaglandin Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    70713-45-0
  • Formula Weight
    292.42
  • Molecular Formula
    C20H24N2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C=CCN1CCN(CC1)C(C=2C=CC=CC2)C=3C=CC=CC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Miyares K, et al. Antagonistic activity of aligeron and papaverine against different smooth muscle stimuli. Methods Find Exp Clin Pharmacol. 1985 Sep;7(9):473-6.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Isbogrel

    Isbogrel (CV4151) is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor that can be used to study cardiac arrhythmias, transient ischemic attacks and thrombosis.

  • 3-O-Acetyl-α-boswell...

    3-O-Acetyl-α-boswellic acid has strong anti-inflammatory activity.

  • Bupivacaine hydrochl...

    Bupivacaine hydrochloride binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells.

Sign In Join Free