Cart
sales@molnova.com
NOC-5
CAS No. 146724-82-5
NOC-5( —— )
Catalog No. M34805 CAS No. 146724-82-5
NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 123 | In Stock |
|
| 5MG | 200 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNOC-5
-
NoteResearch use only, not for human use.
-
Brief DescriptionNOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.
-
DescriptionNOC-5 is a diazeniumdiolate compound that belongs to the same family of NO donors.
-
In VitroNOC-5 (5-20 μM) in PBS led to a rapid increase in NO release on day one.NOC-5 (100 μM, 24 h) activates only caspase-3; an increase in caspase-3 activity occurred after NO donor treatment: 1.62 (1.57-1.66) (P < 0.05). NOC-5 has pro-apoptotic action in Jurkat cells, but at the same time increased the level of anti-apoptotic proteins.
-
In Vivo——
-
Synonyms——
-
PathwayImmunology/Inflammation
-
TargetNOS
-
RecptorNO Synthase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number146724-82-5
-
Formula Weight176.22
-
Molecular FormulaC6H16N4O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=NN(O)N(CCCN)C(C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Sophie A Bradley, et al. Characterisation and comparison of temporal release profiles of nitric oxide generating donors. J Neurosci Methods. 2015 Apr 30;245:116-24.?
molnova catalog
related products
-
Dehydroeburicoic aci...
Dehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload mitochondrial dysfunction and calpain activation in human glioblastomas.
-
EX-A5758
EX-A5758 is a novel putative small molecule nNOS-NOS1AP inhibitor, suppressing inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viability.
-
Cnidicin
Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM).
