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NOC-5
CAS No. 146724-82-5
NOC-5( —— )
Catalog No. M34805 CAS No. 146724-82-5
NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 123 | In Stock |
|
| 5MG | 200 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameNOC-5
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NoteResearch use only, not for human use.
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Brief DescriptionNOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.
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DescriptionNOC-5 is a diazeniumdiolate compound that belongs to the same family of NO donors.
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In VitroNOC-5 (5-20 μM) in PBS led to a rapid increase in NO release on day one.NOC-5 (100 μM, 24 h) activates only caspase-3; an increase in caspase-3 activity occurred after NO donor treatment: 1.62 (1.57-1.66) (P < 0.05). NOC-5 has pro-apoptotic action in Jurkat cells, but at the same time increased the level of anti-apoptotic proteins.
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetNOS
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RecptorNO Synthase
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Research Area——
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Indication——
Chemical Information
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CAS Number146724-82-5
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Formula Weight176.22
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Molecular FormulaC6H16N4O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=NN(O)N(CCCN)C(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sophie A Bradley, et al. Characterisation and comparison of temporal release profiles of nitric oxide generating donors. J Neurosci Methods. 2015 Apr 30;245:116-24.?
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