SAG 21k

CAS No. 946002-48-8

SAG 21k( —— )

Catalog No. M34770 CAS No. 946002-48-8

SAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 275 In Stock
10MG 411 In Stock
25MG 700 In Stock
50MG 918 In Stock
100MG 1349 In Stock
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Biological Information

  • Product Name
    SAG 21k
  • Note
    Research use only, not for human use.
  • Brief Description
    SAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration.
  • Description
    Hh agonist 1 (compound 21k) is a potent Hedgehog (Hh) agonist, with an EC50 0.3 nM. Hh agonist 1 can be used for the research of stroke and other neurological disorders.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Hedgehog (Hh)
  • Recptor
    Hedgehog/Smoothened
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    946002-48-8
  • Formula Weight
    556.07
  • Molecular Formula
    C29H28ClF2N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ClC=1C=2C(SC1C(N(CC3=C(OC)C=CC(=C3)C=4C=CN=CC4)[C@H]5CC[C@H](NC)CC5)=O)=C(F)C=CC2F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Brunton SA, et al. Potent agonists of the Hedgehog signaling pathway. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4308-11. ?
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