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MitoPQ
CAS No. 1821370-28-8
MitoPQ( —— )
Catalog No. M34651 CAS No. 1821370-28-8
MitoPQ (MitoParaquat) is a mitochondria-targeted small molecule compound that selectively enhances mitochondrial superoxide and hydrogen peroxide levels and inhibits insulin-stimulated glucose uptake and translocation of glucose transport protein 4 (GLUT4) to the plasma membrane in adipocytes and myotubes.MitoPQ can be used to MitoPQ can be used to study mitochondrial oxidative stress and regulated GLUT4 transporter.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 93 | In Stock |
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| 10MG | 147 | In Stock |
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| 25MG | 227 | In Stock |
|
| 50MG | 352 | In Stock |
|
| 100MG | 553 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMitoPQ
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NoteResearch use only, not for human use.
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Brief DescriptionMitoPQ (MitoParaquat) is a mitochondria-targeted small molecule compound that selectively enhances mitochondrial superoxide and hydrogen peroxide levels and inhibits insulin-stimulated glucose uptake and translocation of glucose transport protein 4 (GLUT4) to the plasma membrane in adipocytes and myotubes.MitoPQ can be used to MitoPQ can be used to study mitochondrial oxidative stress and regulated GLUT4 transporter.
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DescriptionMitoPQ is a mitochondria-targeted redox cycler. MitoPQ produces superoxide by redox cycling at the flavin site of complex I, selectively increasing superoxide production within mitochondria. MitoPQ can be used in antioxidant study.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptortransporter | Glucokinase
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Research Area——
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Indication——
Chemical Information
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CAS Number1821370-28-8
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Formula Weight954.48
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Molecular FormulaC39H46I3N2P
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 50 mg/mL (52.38 mM; Ultrasonic)DMSO : 33.33 mg/mL (34.92 mM; Ultrasonic )
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SMILESC[N+]1=CC=C(C2=CC=[N+](CCCCCCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)C=C2)C=C1.[I-].[I-].[I-]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Robb EL, et al. Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat. Free Radic Biol Med. 2015 Dec;89:883-94.?
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