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Vasicinone
CAS No. 486-64-6
Vasicinone( —— )
Catalog No. M24440 CAS No. 486-64-6
Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 290 | In Stock |
|
| 10MG | 430 | In Stock |
|
| 25MG | 695 | In Stock |
|
| 50MG | 945 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameVasicinone
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NoteResearch use only, not for human use.
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Brief DescriptionVasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities.
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DescriptionVasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiproliferative activity against human gastric cancer cells MCG-803.
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In VitroVasicinone (1~30 μM; 24 hours; SH-SY5Y cells) significantly reverses the paraquat-induced reduction in cell viability.Vasicinone (10 and 15 μM; 24 hours; SH-SY5Y cells) abates the paraquat-induced injury of SH-SY5Y cells by suppressing the MAPK signaling pathway, dose-dependently reduces the percentage of apoptotic cells and is capable of rescuing paraquat-induced apoptotic death.Vasicinone (10 and 15 μM; SH-SY5Y cells) attenuates the paraquat-induced accumulation of reactive oxygen species (ROS) and attenuates the paraquat-induced expression of apoptotic proteins.Cell Viability Assay Cell Line:SH-SY5Y cells Concentration:1~30 μM Incubation Time:24 hours Result:Significantly reversed the paraquat-induced reduction in cell viability.Western Blot Analysis Cell Line:SH-SY5Y cells Concentration:10 and 15 μM Incubation Time:24 hours Result:Abated the paraquat-induced injury of SH-SY5Y cells by suppressing the MAPK signaling pathway.Apoptosis Analysis Cell Line:SH-SY5Y cells Concentration:10 and 15 μM Incubation Time:24 hours Result:Dose-dependently reduced the percentage of apoptotic cells.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number486-64-6
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Formula Weight202.21
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Molecular FormulaC11H10N2O2
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESC1CN2C(=NC3=CC=CC=C3C2=O)[C@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Antitussive, expectorant, and bronchodilating effects of quinazoline alkaloids (±)-vasicine, deoxyvasicine, and (±)-vasicinone from aerial parts of Peganum harmala L. Phytomedicine. 2015 Nov 15;22(12):1088-95.
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