LM-1685( —— )

Catalog No. M34643 CAS No. 416901-58-1

LM-1685 is a potent and selective inhibitor of COX-2 IN human monocytes and whole blood with IC50 of 0.65μM and IC50 = 4.3μM, respectively, and is a potential compound for the treatment of inflammation.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

LM-1685
Note

Research use only, not for human use.
Brief Description

LM-1685 is a potent and selective inhibitor of COX-2 IN human monocytes and whole blood with IC50 of 0.65μM and IC50 = 4.3μM, respectively, and is a potential compound for the treatment of inflammation.
Description

COX-2-IN-5 (compound 11a) is a potent COX-2 inhibitor with an IC50 value of 0.65 μM. COX-2-IN-5 has the potential for the research of inflammation.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

COX
Recptor

COX
Research Area

——
Indication

——

Chemical Information

CAS Number

416901-58-1
Formula Weight

377.84
Molecular Formula

C18H16ClNO4S
Purity

>98% (HPLC)
Solubility

——
SMILES

C(N1C=2C(C=C1C(OC)=O)=CC(S(C)(=O)=O)=CC2)C3=CC=C(Cl)C=C3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Palomer A, et al. Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models. J Med Chem. 2002 Mar 28;45(7):1402-11.?

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