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Home - Products - Chromatin/Epigenetic - COX - LM-1685

LM-1685

CAS No. 416901-58-1

LM-1685( —— )

Catalog No. M34643 CAS No. 416901-58-1

LM-1685 is a potent and selective inhibitor of COX-2 IN human monocytes and whole blood with IC50 of 0.65μM and IC50 = 4.3μM, respectively, and is a potential compound for the treatment of inflammation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    LM-1685
  • Note
    Research use only, not for human use.
  • Brief Description
    LM-1685 is a potent and selective inhibitor of COX-2 IN human monocytes and whole blood with IC50 of 0.65μM and IC50 = 4.3μM, respectively, and is a potential compound for the treatment of inflammation.
  • Description
    COX-2-IN-5 (compound 11a) is a potent COX-2 inhibitor with an IC50 value of 0.65 μM. COX-2-IN-5 has the potential for the research of inflammation.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    416901-58-1
  • Formula Weight
    377.84
  • Molecular Formula
    C18H16ClNO4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(N1C=2C(C=C1C(OC)=O)=CC(S(C)(=O)=O)=CC2)C3=CC=C(Cl)C=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Palomer A, et al. Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models. J Med Chem. 2002 Mar 28;45(7):1402-11.?
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