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Cipepofol
CAS No. 1637741-58-2
Cipepofol( —— )
Catalog No. M34620 CAS No. 1637741-58-2
Cipepofol (HSK3486) is a GABAA receptor agonist with sedative properties and protective effects in a variety of cardiovascular diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 154 | In Stock |
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| 5MG | 153 | In Stock |
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| 10MG | 238 | In Stock |
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| 25MG | 468 | In Stock |
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| 50MG | 680 | In Stock |
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| 100MG | 1079 | In Stock |
|
| 200MG | 1460 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCipepofol
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NoteResearch use only, not for human use.
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Brief DescriptionCipepofol (HSK3486) is a GABAA receptor agonist with sedative properties and protective effects in a variety of cardiovascular diseases.
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DescriptionCipepofol (Ciprofol), a novel 2,6-disubstituted phenol derivative, is a positive allosteric modulator and direct agonist of the GABAA receptor. Cipepofol can cause the central nerve inhibition and promote sleep based on the structural modification of Propofol (HY-B0649). Cipepofol can activate the sirtuin1 (Sirt1)/Nrf2 pathway. Cipepofol protects the heart against Isoproterenol (ISO; HY-B0468)-induced myocardial infarction by reducing cardiac oxidative stress, inflammatory response and cardiomyocyte apoptosis.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis | GABA Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1637741-58-2
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Formula Weight204.31
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Molecular FormulaC14H20O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (489.45 mM; Ultrasonic )
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SMILES[C@H](C)(C1=C(O)C(C(C)C)=CC=C1)C2CC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ming Lu, et al. Ciprofol: A Novel Alternative to Propofol in Clinical Intravenous Anesthesia? Biomed Res Int. 2023 Jan 19:2023:7443226.?
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