dBRD9 HCl( —— )

Catalog No. M34568 CAS No. 2341840-98-8

dBRD9 HCl is a PROTAC composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide . dBRD9 HCl is a potent and selective degrader of BRD9 (IC50 = 56.6 nM in MOLM-13 cells).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	299	Get Quote
25MG	1222	Get Quote
50MG	1703	Get Quote
100MG	2500	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

dBRD9 HCl
Note

Research use only, not for human use.
Brief Description

dBRD9 HCl is a PROTAC composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide . dBRD9 HCl is a potent and selective degrader of BRD9 (IC50 = 56.6 nM in MOLM-13 cells).
Description

dBRD9 dihydrochloride is a selective BRD9 PROTAC degrader. dBRD9 dihydrochloride inhibits proliferation of AML cell lines.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

Epigenetic Reader Domain
Recptor

Epigenetic Reader Domain
Research Area

——
Indication

——

Chemical Information

CAS Number

2341840-98-8
Formula Weight

856.75
Molecular Formula

C40H47Cl2N7O10
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C1C2=C(C(C3=CC(OC)=C(CN(CC(NCCOCCOCCNC4=CC=CC(C(N5C6C(NC(CC6)=O)=O)=O)=C4C5=O)=O)C)C(OC)=C3)=CN1C)C=CN=C2.Cl.Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Remillard D, Buckley DL, Paulk J, Brien GL, Sonnett M, Seo HS, Dastjerdi S, Wühr M, Dhe-Paganon S, Armstrong SA, Bradner JE. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands. Angew Chem Int Ed Engl. 2017 May 15;56(21):5738-5743.?

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks