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ZEN-3694
CAS No. 1643947-30-1
ZEN-3694( —— )
Catalog No. M34476 CAS No. 1643947-30-1
ZEN-3694 (ZEN 3694) is a bromo-structural domain extra-terminal inhibitor (BETi) with activity in androgen signaling inhibitor (ASI) resistance models and can be used in combination with enzalutamide to study metastatic desmoplasia-resistant prostate cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 93 | Get Quote |
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| 5MG | 140 | Get Quote |
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| 10MG | 227 | Get Quote |
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| 25MG | 403 | Get Quote |
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| 50MG | 642 | Get Quote |
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| 100MG | 888 | Get Quote |
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| 500MG | 1782 | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameZEN-3694
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NoteResearch use only, not for human use.
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Brief DescriptionZEN-3694 (ZEN 3694) is a bromo-structural domain extra-terminal inhibitor (BETi) with activity in androgen signaling inhibitor (ASI) resistance models and can be used in combination with enzalutamide to study metastatic desmoplasia-resistant prostate cancer.
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DescriptionBET-IN-19 (Compound 146) is a BET inhibitor. BET-IN-19 inhibits hlL-6 mRNA transcription (IC50 ≤ 0.3 uM), and c-myc activity in human AML MV4-11 cell (IC50 ≤ 0.3 uM)。BET-IN-19 inhibits tetra-acetylated histone H4 binding to BRD4 bromodomain 1 (IC50 ≤ 0.3 uM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetEpigenetic Reader Domain
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RecptorEpigenetic Reader Domain
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Research Area——
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Indication——
Chemical Information
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CAS Number1643947-30-1
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Formula Weight333.39
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Molecular FormulaC19H19N5O
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Purity>98% (HPLC)
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Solubility——
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SMILESC(N1C=2C(N=C1NC)=NC=C(C2)C=3C(C)=NOC3C)C4=CC=CC=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bryan Cordell DUFFY, et al. Novel bicyclic bromodomain inhibitors. Patent. WO2015002754 A2.
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