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Ticolubant
CAS No. 154413-61-3
Ticolubant( —— )
Catalog No. M34447 CAS No. 154413-61-3
Ticolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migration with an IC50 of 6.6 ± 1.5 nM, and shows topical anti-inflammatory activity in a mouse model of skin inflammation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 319 | Get Quote |
|
| 5MG | 504 | Get Quote |
|
| 10MG | 728 | Get Quote |
|
| 25MG | 1086 | Get Quote |
|
| 50MG | 1463 | Get Quote |
|
| 100MG | 1935 | Get Quote |
|
| 500MG | 3861 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTicolubant
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NoteResearch use only, not for human use.
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Brief DescriptionTicolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migration with an IC50 of 6.6 ± 1.5 nM, and shows topical anti-inflammatory activity in a mouse model of skin inflammation.
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DescriptionTicolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migration with an IC50 of 6.6 ± 1.5 nM, and shows topical anti-inflammatory activity in a mouse model of skin inflammation.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel | LTR
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Research Area——
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Indication——
Chemical Information
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CAS Number154413-61-3
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Formula Weight460.37
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Molecular FormulaC23H19Cl2NO3S
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Purity>98% (HPLC)
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Solubility——
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SMILESC(=C/C(O)=O)\C1=C(OCCC2=CC=CC=C2)C=CC(CSC3=C(Cl)C=CC=C3Cl)=N1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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